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Occurrence in Patients With Mitral Valve Prolapse

Larry M. Baddour, MD; Tony N. Phillips, MD; Alan L. Bisno, MD

Arch Intern Med. 1986;146(1):119-121.

Abstract
Although coagulase-negative staphylococci (CoNS) are frequent etiologic agents in prosthetic valve endocarditis, they rarely infect native heart valves. We report three cases of CoNS endocarditis in patients with mitral valve prolapse (MVP). Review of other reports of MVP-associated endocarditis and of the limited experience with CoNS infection of native heart valves suggests that our experience is not unique. Coagulase-negative staphylococcal endocarditis superimposed on MVP may be difficult to recognize and to treat. The cardiac dysfunction can be quite subtle, the clinical course indolent, the blood culture results difficult to interpret, and the response to antimicrobial agents suboptimal.

(Arch Intern Med 1986;146:119-121)

Author Affiliations
From the Department of Medicine, Division of Infectious Diseases, University of Tennessee Center for the Health Sciences, Memphis.

Footnotes
Accepted for publication April 3,1985.

Reprint requests to Division of Infectious Diseases, University of Tennessee, 956 Court Ave, 3H16, Memphis, TN 38163 (Dr Baddour).

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