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Enayat Niakan, MD; Yadollah Harati, MD; Loren A. Rolak, MD; John P. Comstock, MD; Roxann Rokey, MD

Arch Intern Med. 1986;146(11):2229-2230.

Abstract
• Seventy-three consecutive diabetic adults with symptomatic peripheral neuropathy were evaluated for the presence of cardiovascular autonomic neuropathy and electrocardiographic evidence of myocardial infarction (MI). Twenty-five (34.2%) patients demonstrated cardiovascular autonomic neuropathy, and ten (13.7%) patients had electrocardiographic evidence of MI. Of the ten MI identified, seven were asymptomatic (silent) by history. The incidence of silent MI was significantly higher (P<.04) in patients with cardiovascular autonomic neuropathy. It is postulated that sudden death in diabetic patients with cardiovascular autonomic neuropathy may be due to silent MI.

(Arch Intern Med 1986;146:2229-2230)

Author Affiliations
From the Departments of Neurology (Drs Niakan, Harati, and Rolak) and Medicine (Drs Comstock and Rokey), Baylor College of Medicine and the Veterans Administration Medical Center, Houston.

Footnotes
Accepted for publication March 7, 1986.

Reprint requests to Department of Neurology (NB-302), Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030 (Dr Niakan).

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