 |
|
Intensive Hospital Monitoring Study of Intravenous Cimetidine
Jane B. Porter, MS;
Keith Beard, MB, ChB, MRCP;
Alexander M. Walker, MD, DrPH;
David H. Lawson, MD, FRCP;
Hershel Jick, MD;
Gavin S. M. Kellaway, MD
Arch Intern Med. 1986;146(11):2237-2239.
Abstract
• We studied the frequency of adverse reactions occurring in 1189 patients who received cimetidine intravenously, based on data collected as part of a hospital-based monitoring study of recently marketed drugs. There were 40 patients (3.4%) with adverse reactions, 23 of whom were considered to be "definitely" or "probably" related to cimetidine use and 17 patients in whom a causal association was possible. The most frequently reported reactions were neuropsychiatric disorders in 19 patients (1.6%) and leukopenia in eight patients (0.7%).
(Arch Intern Med 1986;146:2237-2239)
Author Affiliations
From the Boston Collaborative Drug Surveillance Program, Boston University Medical Center, Waltham, Mass (Ms Porter, Drs Beard, Walker, and Jick), the Department of Epidemiology, Harvard School of Public Health, Boston (Dr Walker), the Royal Infirmary, Glasgow, Scotland (Dr Lawson), and Auckland (New Zealand) Hospital (Dr Kellaway).
Footnotes
Accepted for publication Feb 25, 1986.
Reprint requests to Boston Collaborative Drug Surveillance Program, 400-1 Totten Pond Rd, Waltham, MA 02154 (Dr Jick).
 CiteULike  Connotea  Delicious  Digg  Facebook  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Cimetidine as adjunctive treatment for acetaminophen overdose
Burkhart et al.
Hum Exp Toxicol 1995;14:299-304.
ABSTRACT
Report on Other Drug Use Among Persons Previously Reported to Have Received Intravenous Cimetidine
Jick
Arch Intern Med 1992;152:2145-2145.
ABSTRACT
Central Nervous System Reactions to Histamine-2 Receptor Blockers
Cantu and Korek
ANN INTERN MED 1991;114:1027-1034.
ABSTRACT
Histamine2-Receptor Antagonists and Cardiovascular Drugs-Reply
Lipsy et al.
Arch Intern Med 1991;151:815-815.
ABSTRACT
Unrecognized Drug Interactions With Famotidine and Nizatidine
Karlstadt and Palmer
Arch Intern Med 1991;151:810-814.
ABSTRACT
|
