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Use of Tetracyclines vs Rifampin

Sam T. Donta, MD; Philip W. Smith, MD; Robert E. Levitz, MD; Richard Quintiliani, MD

Arch Intern Med. 1986;146(5):902-904.

Abstract
• We describe four patients with Mycobacterium marinum infections who did not respond to two- to six-week courses of therapy with tetracycline, minocycline, and doxycycline. All four patients had prompt responses to therapy with either rifampin alone (two patients) or rifampin in combination with ethambutol. Results of antimicrobial sensitivity tests may be helpful in guiding therapy. Rifampin may be the drug of choice for treatment of these infections.

(Arch Intern Med 1986;146:902-904)

Author Affiliations
From the University of Connecticut School of Medicine, Farmington (Drs Donta, Levitz, and Quintiliani); University of Nebraska School of Medicine and Bishop Clarkson Hospital, Omaha (Dr Smith); Newington (Conn) Veterans Administration Medical Center (Dr Donta); and the Hartford (Conn) Hospital (Drs Levitz and Quintiliani).

Footnotes
Accepted for publication Aug 12, 1985.

Reprint requests to Medical Service, Veterans Administration Medical Center, Newington, CT 06111 (Dr Donta).

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