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A Prospective Controlled Study

Jacob Korula, MD; Ahmet Baydur, MD; Catherine Sassoon, MD; Ivan Sakimura, MD

Arch Intern Med. 1986;146(8):1517-1520.

Abstract
• A prospective, controlled study to determine the short- and long-term effects of esophageal variceal sclerotherapy (EVS) on lung function was carried out on 11 patients with cirrhotic portal hypertension and variceal hemorrhage. Eleven patients with chronic liver disease undergoing diagnostic endoscopy served as controls. There was no difference in lung function tests and gas exchange in both the EVS or control groups after either procedure. No change in these parameters was noted during follow-up on continued sclerotherapy in the EVS group. Ventilation-perfusion scans and chest roentgenograms, performed before and after EVS, demonstrated no significant change. We conclude that in patients with stable liver disease and without hepatic failure, EVS does not result in serious short- or long-term impairment of lung function.

(Arch Intern Med 1986;146:1517-1520)

Author Affiliations
From the Hepatology (Dr Korula) and Pulmonary (Drs Baydur and Sasson) Divisions, Departments of Medicine and Nuclear Medicine (Dr Sakimura), University of Southern California at Rancho Los Amigos Hospital, Downey, Calif.

Footnotes
Accepted for publication Jan 2, 1986.

Reprints not available.

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