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Changes in a Patient With Hypertension and Unilateral Renal Artery Stenosis

Gijsbert G. Geyskes, MD; H. Yoe Oei, MD; Carl B. A. J. Puylaert, MD; Evert J. Dorhout Mees, MD

Arch Intern Med. 1986;146(9):1705-1708.

Abstract
• In a 56-year-old man with severe familial hypertension and unilateral renal artery stenosis, captopril induced striking changes in the renograms of the affected kidney. After injection of orthoiodohippurate sodium I 131, the uptake phase was unchanged but the later curve showed continuous accumulation. In contrast, the uptake of technetium Tc 99m diethylenetriamine pentracetic acid was abolished. These changes are compatible with a cessation of filtration and maintenance of renal blood flow. After balloon dilatation of the stenosis, the blood pressure became lower, and these changes could no longer be demonstrated. The captopril renogram may provide useful information on the dependency of hypertension on unilateral renal artery stenosis.

(Arch Intern Med 1986;146:1705-1708)

Author Affiliations
From the Department of Nephrology and Hypertension, University Hospital, Utrecht, the Netherlands.

Footnotes
Accepted for publication Nov 27, 1985.

Reprint requests to Department of Nephrology and Hypertension, University Hospital, Catharijnesingel 101, 3511 GV Utrecht, the Netherlands (Dr Geyskes).

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ABSTRACT