This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Francisco Escobedo, MD; Pedro Penagos, MD; Jesus Rodriguez, MD; Julio Sotelo, MD

Arch Intern Med. 1987;147(4):738-741.

Abstract
• Seven patients with chronic parenchymal brain cysticercosis were treated with albendazole for one month at daily doses of 15 mg/kg of body weight. Computed tomographic follow-up studies were made at the following times: a mean of 16 months before the trial; the beginning of treatment; the end of treatment; and three months afterward. Computed tomographic studies at the beginning of treatment showed a total of 157 cysts, the last day of treatment the number had decreased to 39 cysts, and three months later, the total number of lesions was 22; this represents 86% improvement in the number of cystic lesions. Control studies in the same group of patients had shown chronic persistence of lesions without spontaneous improvement in most cases. Two patients had been treated with praziquantel previously with partial response; in both cases albendazole therapy was effective with 100% and 77% improvement. We conclude that albendazole is highly effective for the treatment of parenchymal brain cysticercosis. It is also effective in patients who had shown poor therapeutic response to praziquantel.

(Arch Intern Med 1987;147:738-741)

Author Affiliations
From the Research Division, National Institute of Neurology and Neurosurgery of Mexico, Mexico City.

Footnotes
Accepted for publication Sept 10, 1986.

Reprint requests to Instituto Nacional de Neurología y Neurocirugía, Insurgentes sur 3877, 14410 Mexico 22, DF (Dr Sotelo).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Neurocysticercosis: some of the essentials
Garcia et al.
PN 2006;6:288-297.
FULL TEXT  

Meta-Analysis: Cysticidal Drugs for Neurocysticercosis: Albendazole and Praziquantel
Del Brutto et al.
ANN INTERN MED 2006;145:43-51.
ABSTRACT | FULL TEXT  

Topical Review: Neurocysticercosis in Children
Singhi and Singhi
J Child Neurol 2004;19:482-492.
ABSTRACT  

Current Consensus Guidelines for Treatment of Neurocysticercosis
Garcia et al.
Clin. Microbiol. Rev. 2002;15:747-756.
ABSTRACT | FULL TEXT  

Medical Treatment for Neurocysticercosis Characterized by Giant Subarachnoid Cysts
Proano et al.
NEJM 2001;345:879-885.
ABSTRACT | FULL TEXT  

Clinical Spectrum of 500 Children With Neurocysticercosis and Response to Albendazole Therapy
Singhi et al.
J Child Neurol 2000;15:207-213.
ABSTRACT  

Is the Course of Neurocysticercosis Modified by Treatment With Anthelmintic Agents?
Del Brutto
Arch Intern Med 1997;157:128-129.
ABSTRACT  

Is the Course of Neurocysticercosis Modified by Treatment With Antihelminthic Agents?
Carpio et al.
Arch Intern Med 1995;155:1982-1988.
ABSTRACT  

Medical Treatment of Cysticercosis--Effective
Del Brutto
Arch Neurol 1995;52:102-104.
ABSTRACT  

Letters to the Editor
Dick et al.
The Journal of the Royal Society for the Promotion of Health 1993;113:50-51.
 

Albendazole Therapy for Giant Subarachnoid Cysticerci
Brutto et al.
Arch Neurol 1992;49:535-538.
ABSTRACT  

Therapy for Neurocysticercosis: Comparison Between Albendazole and Praziquantel
Takayanagui and Jardim
Arch Neurol 1992;49:290-294.
ABSTRACT  

Albendazole Therapy for Neurocysticercosis
Del Brutto
Arch Neurol 1990;47:1278-1278.
ABSTRACT  

Albendazole Therapy for Neurocysticercosis-Reply
Alarcon
Arch Neurol 1990;47:1278-1279.
ABSTRACT  

Antihelminthic Therapy for Neurocysticercosis-Reply
Alarcon et al.
Arch Neurol 1990;47:1060-1060.
ABSTRACT  

Neurocysticercosis: Short Course of Treatment With Albendazole
Alarcon et al.
Arch Neurol 1989;46:1231-1236.
ABSTRACT  

Short Course of Albendazole Therapy for Neurocysticercosis
Sotelo et al.
Arch Neurol 1988;45:1130-1133.
ABSTRACT  

Neurocysticercosis: Two Hundred Thirty-Eight Cases From a California Hospital
Scharf
Arch Neurol 1988;45:777-780.
ABSTRACT  

Albendazole vs Praziquantel for Therapy for Neurocysticercosis: A Controlled Trial
Sotelo et al.
Arch Neurol 1988;45:532-534.
ABSTRACT  

Sex-Related Severity of Inflammation in Parenchymal Brain Cysticercosis
Del Brutto et al.
Arch Intern Med 1988;148:544-546.
ABSTRACT