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John F. Aloia, MD; Ashok N. Vaswani, MD; James K. Yeh, PhD; Stanton H. Cohn, PhD

Arch Intern Med. 1988;148(1):121-123.

Abstract
• The relationship between physical activity and bone mass was investigated in 24 healthy, white, premenopausal women (mean age [±SE], 39.0±1.39 years). Physical activity was determined by a sensor that measures movement of the trunk, and bone mineral levels were determined by means of singleand dual-photon absorptiometry and neutron activation analysis. Total physical activity levels were related both to bone mineral density of the spine (r=.41) and to total body calcium levels (r=.51). There was no significant relationship between the bone density of the distal portion of the radius and activity (r=.20). Nonparametric analysis and stepwise multiple regression analysis revealed negative correlations between cigarette smoking and bone density of the spine and radius. These data suggest that the level of physical activity in sedentary white women may be a determinant of peak total skeletal mass and bone density of the spine.

(Arch Intern Med 1988;148:121-123)

Author Affiliations
From the Department of Medicine, Winthrop-University Hospital, Mineola, NY (Drs Aloia, Vaswani, and Yeh); the Brookhaven National Laboratory, Upton, NY (Dr Cohn); and the Health Sciences Center, School of Medicine, State University of New York at Stony Brook (Drs Aloia, Vaswani, and Yeh).

Footnotes
Accepted for publication Sept 18, 1987.

Reprint requests to Department of Medicine, Winthrop-University Hospital, 259 First St, Mineola, NY 11501 (Dr Aloia).

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