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Ronald Klein, MD; Barbara E. K. Klein, MD; Scot Moss, MA; David L. DeMets, PhD

Arch Intern Med. 1988;148(1):181-186.

Abstract
• In a population-based study in southern Wisconsin, 1370 diabetic persons diagnosed after 29 years of age were examined using standard protocols to determine the prevalence of proteinuria and associated risk variables. Proteinuria (0.30 g/L) was present in 18.0% of persons taking insulin and 12.2% of the persons not taking insulin. Proliferative retinopathy and proteinuria were associated with each other. Proteinuria was also associated with increasing duration of diabetes, high systolic blood pressure, use of digoxin, and being male, but not with a history of cigarette smoking or metabolic control as measured by glycosylated hemoglobin.

(Arch Intern Med 1988;148:181-186)

Author Affiliations
From the Department of Ophthalmology, University of Wisconsin Medical School, Madison.

Footnotes
Accepted for publication Sept 18, 1987.

Reprint requests to Department of Ophthalmology, Clinical Sciences Center, 600 Highland Ave, Madison, WI 53792 (Dr R. Klein).

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