This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (117)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

J. Thomas Danzi, MD

Arch Intern Med. 1988;148(2):297-302.

Abstract
• Ulcerative colitis and Crohn's disease have reported associations with a spectrum of extraintestinal diseases. This association has been appropriately termed as extraintestinal manifestations because large case studies have demonstrated that between 25% to 36% of patients with either type of inflammatory bowel disease will have at least one such associated disease. The spectrum of diseases reported associated with either ulcerative colitis or Crohn's disease involves many organ systems. Some of these extraintestinal manifestations are related to active colitis—joint, skin, ocular, and oral; small bowel dysfunction—cholelithiasis and nephrolithiasis; and nonspecific manifestations such as amyloidosis and hepatobiliary diseases. The purpose of this review is to update the clinicians with the most recent literature concerning the etiology, clinical course and the therapy of the extraintestinal manifestations associated with both forms of idiopathic inflammatory bowel disease.

(Arch Intern Med 1988;148:297-302)

Author Affiliations
From the Section of Gastroenterology, Guthrie Medical Center, Sayre, Pa.

Footnotes
Accepted for publication Oct 15, 1987.

Reprints not available.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Prospective Comparison of State-of-the-Art MR Enterography and CT Enterography in Small-Bowel Crohn's Disease
Siddiki et al.
Am. J. Roentgenol. 2009;193:113-121.
ABSTRACT | FULL TEXT  

Stridor in crohn disease and the use of infliximab.
Kirkcaldy et al.
Chest 2006;130:579-581.
ABSTRACT | FULL TEXT  

Important cutaneous manifestations of inflammatory bowel disease
Trost and McDonnell
Postgrad. Med. J. 2005;81:580-585.
ABSTRACT | FULL TEXT  

Tumour necrosis factor-{alpha} inhibitors and the reactivation of latent tuberculosis infection
Long and Gardam
CMAJ 2003;168:1153-1156.
FULL TEXT  

Prevalence of subclinical anterior uveitis in adult patients with inflammatory bowel disease
Verbraak et al.
Br J Ophthalmol 2001;85:219-221.
ABSTRACT | FULL TEXT  

Case 21-2000- A 13-Year-Old Boy with Genital Edema and Abdominal Pain
Tracy and Graeme-Cooke
NEJM 2000;343:127-133.
FULL TEXT  

Experimental colitis increases blood-brain barrier permeability in rabbits
Hathaway et al.
Am. J. Physiol. Gastrointest. Liver Physiol. 1999;276:G1174-G1180.
ABSTRACT | FULL TEXT  

Multiple Cerebral Venous Thromboses In a Child with Ulcerative Colitis
Calderon et al.
CLIN PEDIATR 1993;32:169-171.
 

Vulvar Erythema and Induration
Patton et al.
Arch Dermatol 1990;126:1351-1352.
ABSTRACT  

Coexistence of Pyoderma Gangrenosum and Arteritis in Ulcerative Colitis
MASUDA and OZEKI
Arch Intern Med 1989;149:1226-1226.
ABSTRACT