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Hyperthyroidism Following HypothyroidismData on Six Cases
Vahab Fatourechi, MD;
Hossein Gharib, MD
Arch Intern Med. 1988;148(4):976-978.
Abstract
Hypothyroidism complicated by spontaneous hyperthyroidism is an interesting but rare occurrence in the spectrum of autoimmune thyroid disorders. We report data on six patients who had hyperthyroidism two to 20 years (mean, eight years) after the diagnosis of hypothyroidism. In three patients, triiodothyronine toxicosis accounted for the hyperthyroid symptoms. The presence of thyroid antibodies and lymphocytic infiltration in the thyroid gland points to an autoimmune mechanism. It is believed that this phenomenon occurs more often than is recognized.
(Arch Intern Med 1988;148:976-978)
Author Affiliations
From the Division of Endocrinology, Metabolism, and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minn.
Footnotes
Accepted for publication Dec 3, 1987.
Reprint requests to Mayo Clinic, 200 First St SW, Rochester, MN 55905 (Dr Gharib).
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ABSTRACT
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