 |
|
Tetracycline for Sclerosis of Thyroid CystsA Randomized Study
Laszlo Hegedüs, MD;
Jens Mølhom Hansen, MD;
Steen Karstrup, MD;
Søren Torp-Pedersen, MD;
Niels Juul, MD
Arch Intern Med. 1988;148(5):1116-1118.
Abstract
• In a prospective study, 53 consecutive patients with solitary thyroid cysts were randomized to ultrasonically guided cyst aspiration and subsequent flushing with isotonic saline (n=30) or tetracycline hydrochloride (n=23). The patients were followed up clinically and ultrasonically 1, 3, 6, and 12 months after treatment. If the cyst recurred, a repeated treatment was offered. Cure was defined as the absence of any residual nodule and an ultrasonic cyst volume of less than 1 mL 12 months after the last treatment. During follow-up, two patients without recurrence after saline treatment and six patients without recurrence after tetracycline treatment developed solid cold nodules. Fourteen (47%) of 30 patients in the saline group and ten (43%) of 23 patients in the tetracycline group were cured (not statistically significant). Tetracycline does not seem to offer any advantage over isotonic saline in the treatment of thyroid cysts, and some of these patients still need thyroid surgery.
(Arch Intern Med 1988;148:1116-1118)
Author Affiliations
From the Departments of Internal Medicine and Endocrinology F (Drs Hegedüs and Hansen) and Ultrasound (Drs Karstrup, Torp-Pedersen, and Juul), Herlev (Denmark) Hospital.
Footnotes
Accepted for publication Dec 3, 1987.
Reprint requests to Department of Internal Medicine and Endocrinology F, Herlev Hospital, DK-2730 Herlev, Denmark (Dr Hegedüs).
 CiteULike  Connotea  Delicious  Digg  Facebook  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
|
Non-surgical management of benign thyroid cysts: use of ultrasound-guided ethanol ablation
Kanotra et al.
Postgrad. Med. J. 2008;84:639-643.
ABSTRACT
| FULL TEXT
Percutaneous Ethanol Injection for Benign Cystic Thyroid Nodules: Is Aspiration of Ethanol-Mixed Fluid Advantageous?
Kim et al.
Am. J. Neuroradiol. 2005;26:2122-2127.
ABSTRACT
| FULL TEXT
Treatment of Recurrent Thyroid Cysts with Ethanol: A Randomized Double-Blind Controlled Trial
Bennedbaek and Hegedus
J. Clin. Endocrinol. Metab. 2003;88:5773-5777.
ABSTRACT
| FULL TEXT
Efficacy of Sonographically Guided Percutaneous Ethanol Injection for Treatment of Thyroid Cysts Versus Solid Thyroid Nodules
Kim et al.
Am. J. Roentgenol. 2003;180:1723-1726.
ABSTRACT
| FULL TEXT
Management of Simple Nodular Goiter: Current Status and Future Perspectives
Hegedus et al.
Endocr Rev 2003;24:102-132.
ABSTRACT
| FULL TEXT
Sonographically Guided Ethanol Sclerotherapy for Benign Thyroid Cysts: Results in 22 Patients
Cho et al.
Am. J. Roentgenol. 2000;174:213-216.
ABSTRACT
| FULL TEXT
Treatment of Recurrent Thyroid Cysts by Injection of Tetracycline or Minocycline
Lee et al.
Arch Intern Med 1989;149:599-601.
ABSTRACT
|
