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Pefloxacin Treatment of Meningitis Caused by Gram-negative Bacteria
Shlomo Segev, MD;
Asher Barzilai, MD;
Nechama Rosen;
Gila Joseph;
Ethan Rubinstein, MD
Arch Intern Med. 1989;149(6):1314-1316.
Abstract
• Ten patients with acute meningitis caused by gram-negative bacteria were treated with pefloxacin intravenously for a mean period of 10 days. Eight patients responded clinically to pefloxacin treatment, and the causative organisms were eradicated from the cerebrospinal fluid in 9 of the 10 patients. Pefloxacin may offer a new, efficacious, and safe therapy for gram-negative meningitis.
(Arch Intern Med. 1989;149:1314-1316)
Author Affiliations
From the Infectious Diseases Unit, Chaim Sheba Medical Center, Tel-Aviv University Medical School, Tel-Hashomer, Israel.
Footnotes
Accepted for publication June 30, 1988.
Reprint requests to Infectious Diseases Unit, Chaim Sheba Medical Center, Tel-Hashomer 52621, Israel (Dr Segev).
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