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Diabetic NephropathyAn Update
Alluru S. Reddi, MD, PhD;
Rafael A. Camerini-Davalos, MD, DSc
Arch Intern Med. 1990;150(1):31-43.
Abstract
Nephropathy is a serious microvascular complication in patients with insulin-dependent diabetes mellitus. In the United States, diabetes accounts for one fourth of new cases of end-stage renal disease each year. Complication rates and costs are much higher for diabetic than for nondiabetic patients with end-stage renal disease. Despite numerous studies, the pathophysiology of diabetic renal disease is not completely understood. We reviewed the current status of the structural, functional, biochemical, pathogenetic, and treatment modalities of diabetic renal disease and examined future therapeutic interventions.
(Arch Intern Med. 1990;150:31-43)
Author Affiliations
From the Division of Nephrology, Department of Medicine, University of Medicine and Dentistry–New Jersey Medical School, Newark (Dr Reddi); and the Department of Medicine, Metropolitan Hospital Research Center, New York, NY (Dr Camerini-Davalos).
Footnotes
Accepted for publication March 15,1989.
Reprint requests to Department of Medicine, UMD-New Jersey Medical School, 185 S Orange Ave, Newark, NJ 07103-2757 (Dr Reddi).
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