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Parvovirus B19–Associated Hemophagocytic Syndrome
Susan E. Boruchoff, MD;
Bruce A. Woda, MD;
German A. Pihan, MD;
William A. Durbin, MD;
Dina Burstein, MD;
Neil R. Blacklow, MD
Arch Intern Med. 1990;150(4):897-899.
Abstract
• Parvovirus B19 is a recently described pathogen, associated with an increasing spectrum of clinical manifestations. We present the first reported case, to our knowledge, of parvovirus B19–associated hemophagocytic syndrome, in which the diagnosis of parvovirus infection was documented by the presence of B19-specific IgM and IgG antibodies. Pancytopenia resolved immediately following splenectomy and the patient recovered completely.
(Arch Intern Med. 1990;150:897-899)
Author Affiliations
From the Departments of Medicine, Division of Infectious Diseases (Drs Boruchoff and Blacklow), Pathology (Drs Woda and Pihan), and Pediatrics (Drs Durbin and Burstein), University of Massachusetts Medical Center, Worcester.
Footnotes
Accepted for publication December 29,1989.
Dr Burstein is now with The New York (NY) Hospital.
Reprint requests to the Division of Infectious Diseases, University of Massachusetts Medical Center, 55 Lake Ave N, Worcester, MA 01655 (Dr Blacklow).
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