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The French Tricolor

John H. Klippel, MD

Arch Intern Med. 1991;151(12):2389-2393.

Abstract
Recent epidemiologic surveys indicate that episodic vasospasm of arterioles (Raynaud's phenomenon) is a common finding in the general population. In a small minority of these individuals, an underlying, often reversible cause or systemic disease associated with vasospasm can be identified. The range of these so-called secondary forms of vasospasm is broad and includes systemic rheumatic syndromes, vibration-induced vascular injury, drug-induced vasospasm, and infectious disorders. Several different physiologic mechanisms may be responsible for vasospasm; hyperactivity of the sympathetic nervous system and abnormal adrenergic receptor function appear to be most important.

(Arch Intern Med. 1991;151:2389-2393)

Author Affiliations
From the Arthritis and Rheumatism Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, Md.

Footnotes
Accepted for publication July 31, 1991.

Reprint requests to the National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bldg 10, Room 9N228, Bethesda, MD 20892 (Dr Klippel).

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