This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (8)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

The Framingham Study

Bernard E. Kreger, MD, MPH; Keaven M. Anderson, PhD; Daniel Levy, MD

Arch Intern Med. 1991;151(7):1365-1368.

Abstract
The Framingham Study cohort of 5209 white men and women was examined to determine the long-term incidence of manifestations of new coronary heart disease as a function of QRS interval on subjects' baseline electrocardiograms (recorded at the 9th biennial examination). Over 18 years of follow-up, age-adjusted incidence of myocardial infarction, angina pectoris, and coronary death appeared unrelated to baseline QRS prolongation in both sexes, by Cox regression. Subjects with left bundlebranch block fared no worse than those with right pattern. These relations held whether or not subjects with baseline electrocardiographic abnormalities other than intraventricular block were excluded from consideration. In sum, QRS duration is an unimportant predictor of coronary disease in this Framingham population.

(Arch Intern Med. 1991;151:1365-1368)

Author Affiliations
From the Sections of General Internal Medicine and of Preventive Medicine and Epidemiology, the Evans Memorial Department of Clinical Research, Boston (Mass) University Medical Center (Dr Kreger), and the National Heart, Lung, and Blood Institute of the National Institutes of Health, Framingham, Mass (Drs Anderson and Levy).

Footnotes
Accepted for publication February 18, 1991.

Presented, in part, at the 28th Annual Conference on Cardiovascular Disease Epidemiology, Santa Fe, NM, March 17, 1988.

Reprint requests to University Hospital, 88 E Newton St, Boston, MA 02118 (Dr Kreger).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Kidney Function, Electrocardiographic Findings, and Cardiovascular Events among Older Adults
Kestenbaum et al.
CJASN 2007;2:501-508.
ABSTRACT | FULL TEXT  

PROLONGED QRS INTERVAL APPEARS BENIGN IN PATIENTS WITHOUT CLINICAL HEART DISEASE
JWatch General 1991;1991:5-5.
FULL TEXT