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John J. Bullen, PhD, MRCVS; Paul B. Spalding; C. Gillon Ward, MD; John M. C. Gutteridge, PhD, DSc

Arch Intern Med. 1991;151(8):1606-1609.

Abstract
Vibrio vulnificus is killed by normal human blood but grows rapidly in blood from patients with hemochromatosis. It also grows in normal blood if the saturation of the transferrin is increased or if hematin, which contains iron, is added. It is suggested that the increased availability of iron in the blood of patients with chronic iron overload is responsible for their enhanced susceptibility to infection with V vulnificus.

(Arch Intern Med. 1991;151:1606-1609)

Author Affiliations
From the Department of Surgery, University of Miami (Fla) School of Medicine (Drs Bullen and Ward and Mr Spalding); and the National Institute for Biological Standards and Control, London, England (Dr Gutteridge).

Footnotes
Accepted for publication January 22, 1991.

Reprint requests to Department of Surgery (R-310A), University of Miami School of Medicine, PO Box 016310, Miami, FL 33101 (Dr Bullen).

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