 |
|
latrogenic Renal Disease
Morris Davidman, MD, FRCP;
Paul Olson, MD;
Jeffrey Kohen, MD;
Tom Leither, MD;
Carl Kjellstrand, MD, PhD, FRCPC
Arch Intern Med. 1991;151(9):1809-1812.
Abstract
| |
We studied iatrogenic problems in nephrology by classifying all patients for nephrology consultation into nine presenting syndromes and seven etiologic groups. One hundred (2.2%) of all admissions were seen in nephrology consultation. Acute renal failure was the most common presenting syndrome, accounting for 59% of the consultations. Fortyone of the 100 consultations (1% of all admissions) had a renewal syndrome of iatrogenic origin. Of these 41 patients, 38 had acute renal failure and three had fluid and electrolyte problems. Twenty of the 41 patients had drug-induced problems. Eighteen of these patients were dehydrated, and in three patients, acute renal failure occurred after surgery. Of the 20 patients with iatrogenic renal problems caused by drugs, seven problems were antibiotic related, five were due to diuretics, four were due to nonsteroidal antiinflammatory drugs, three were due to angiotensinconverting enzyme inhibitors, and one was from the use of contrast medium. The 41 patients with iatrogenic-related renal disease were older than the other 59 patients (61.8 vs 49.3 years). latrogenic renal disease developed in 1% of all patients admitted to a tertiary care hospital, and 12% of these patients died. The most common renal syndrome is acute renal failure, most often caused by nephrotoxic drugs. The incidence can probably be decreased by better monitoring of body weight and fluid balance to prevent dehydration and by the avoidance of nephrotoxic drugs.
(Arch Intern Med. 1991;151:1809-1812)
Author Affiliations
From the Nephrology Division, Department of Medicine, Hennepin County Medical Center, Minneapolis, Minn (Drs Davidman, Olson, Kohen, and Leither); and the Nephrology Division, Department of Medicine, University of Alberta Hospital, Edmonton (Dr Kjellstrand).
Footnotes
Accepted for publication March 21, 1991.
Presented in part at the meeting of the American Society of Nephrology, Washington, DC, December 11-14, 1988.
Reprint requests to Nephrology Division, Department of Medicine, 2E3.31 Walter Mackenzie Centre, University of Alberta Hospital, Edmonton, Alberta, Canada T6G 2B7 (Dr Kjellstrand).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
|
Long-term Risk of Mortality and End-Stage Renal Disease Among the Elderly After Small Increases in Serum Creatinine Level During Hospitalization for Acute Myocardial Infarction
Newsome et al.
Arch Intern Med 2008;168:609-616.
ABSTRACT
| FULL TEXT
Renal Failure Secondary to Acute Tubular Necrosis: Epidemiology, Diagnosis, and Management
Gill et al.
Chest 2005;128:2847-2863.
ABSTRACT
| FULL TEXT
Natriuretic peptides and acute renal failure
Vesely
Am. J. Physiol. Renal Physiol. 2003;285:F167-F177.
ABSTRACT
| FULL TEXT
Diuretics, Mortality, and Nonrecovery of Renal Function in Acute Renal Failure
Mehta et al.
JAMA 2002;288:2547-2553.
ABSTRACT
| FULL TEXT
Non-specialist management of acute renal failure
Stevens et al.
QJM 2001;94:533-540.
ABSTRACT
| FULL TEXT
Preventable Medical Injuries in Older Patients
Rothschild et al.
Arch Intern Med 2000;160:2717-2728.
ABSTRACT
| FULL TEXT
Iatrogenic Diseases as a Reason for Admission to the Intensive Care Unit: Incidence, Causes, and Consequences
Darchy et al.
Arch Intern Med 1999;159:71-78.
ABSTRACT
| FULL TEXT
Acute Oliguria
Klahr and Miller
NEJM 1998;338:671-675.
FULL TEXT
Nonsteroidal Anti-inflammatory Agents and Acute Renal Failure
Arch Intern Med 1996;156:2414-2414.
ABSTRACT
Acute Renal Failure
Thadhani et al.
NEJM 1996;334:1448-1460.
FULL TEXT
IATROGENIC RENAL DISEASE
JWatch General 1991;1991:4-4.
FULL TEXT
|
