This Article  • References  • Full text PDF  • Correction  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (66)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Linda M. Gerber, PhD; Celia Shmukler, MD; Michael H. Alderman, MD

Arch Intern Med. 1992;152(2):373-377.

Abstract
Eighty-one normotensive and 61 hypertensive white and nonwhite subjects were studied cross-sectionally to determine the prevalence and determinants of elevated urinary albumin levels. Twenty-four-hour urinary albumin excretion was determined by radioimmunoassay. The prevalence of elevated urinary albumin level (15 mg/24 h) was significantly greater in hypertensive than in normotensive subjects (31.1% and 8.6%). Among hypertensive subjects, a much greater proportion of whites than nonwhites had urinary albumin levels of 15 mg/24 h or greater (39.5% and 17.4%). The independent association of blood pressure with urinary albumin level was affirmed by logistic regression analyses for white normotensive and hypertensive subjects combined, and for hypertensive subjects alone. Furthermore, among hypertensive subjects, whites were five times as likely as nonwhites to have elevated urinary albumin levels. Thus, blood pressure and ethnicity were the important determinants of urinary albumin excretion among hypertensive subjects.

(Arch Intern Med. 1992;152:373-377)

Author Affiliations
From the Cardiovascular Center and Department of Medicine, The New York (NY) Hospital-Cornell University Medical College (Dr Gerber); and Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY (Drs Shmukler and Alderman).

Footnotes
Accepted for publication August 23, 1991.

Reprint requests to Cardiovascular Center, The New York Hospital-Cornell University Medical College, 525 E 68th St, Starr 4, New York, NY 10021 (Dr Gerber).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Racial Differences in Microalbumin Excretion in Healthy Adolescents
Hanevold et al.
Hypertension 2008;51:334-338.
ABSTRACT | FULL TEXT  

Microalbuminuria and chronic kidney disease as risk factors for cardiovascular disease
Sarafidis and Bakris
Nephrol Dial Transplant 2006;21:2366-2374.
FULL TEXT  

Long-Term Impact of Systolic Blood Pressure and Glycemia on the Development of Microalbuminuria in Essential Hypertension
Pascual et al.
Hypertension 2005;45:1125-1130.
ABSTRACT | FULL TEXT  

Factors Related to the Occurrence of Microalbuminuria During Antihypertensive Treatment in Essential Hypertension
Redon et al.
Hypertension 2002;39:794-798.
ABSTRACT | FULL TEXT  

Influence of the I/D Polymorphism of the Angiotensin-Converting Enzyme Gene on the Outcome of Microalbuminuria in Essential Hypertension
Redon et al.
Hypertension 2000;35:490-495.
ABSTRACT | FULL TEXT  

Albumin Excretion Rate Increases During Acute Myocardial Infarction and Strongly Predicts Early Mortality
Berton et al.
Circulation 1997;96:3338-3345.
ABSTRACT | FULL TEXT  

Albuminuria in Association With Insulin and Sodium-Lithium Countertransport in Young African Americans With Borderline Hypertension
Falkner et al.
Hypertension 1995;25:1315-1321.
ABSTRACT | FULL TEXT