Coffee and Coronary Heart Disease

doi:10.1001/archinte.1992.00400210009002

You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.

Vol. 152 No. 9, SEPTEMBER 1992

Online Only
	•	Online First Table of Contents

REVIEW ARTICLE

•	Online Features

This Article
•	References
•	Full text PDF
•	Reply to article
•	Send to a friend
•	Save in My Folder
•	Save to citation manager
•	Permissions

Citing Articles
•	Citation map
•	Citing articles on HighWire
•	Citing articles on Web of Science (63)
•	Contact me when this article is cited

Related Content
•	Similar articles in this journal

Social Bookmarking
	What's this?

Coffee and Coronary Heart Disease

Martin G. Myers, MD, FRCPC; Antoni Basinski, MD, PhD, CCFP

Arch Intern Med. 1992;152(9):1767-1772.

Abstract

Objective.—
We determined if coffee consumption is associated with an increasedrisk of developing coronary heart disease.

Data Identification.—
Articles published between 1966 and August 1991 examining apossible link between coffee and coronary heart disease wereidentified by a computeraided literature search (Medline) andby standard bibliographic searches.

Study Selection.—
All prospective cohort studies providing data on daily coffeeconsumption and coronary events (acute myocardial infarctionand/or coronary death) were included.

Data Extraction.—
Data from each published article were extracted. Additionalunpublished data augmenting those published for one study werealso included. Each cohort was categorized by reported dailycoffee consumption. Incidence of coronary events at each levelof coffee consumption was the primary outcome.

Results.—
Eleven prospective studies were included. The coronary eventsfor subjects consuming little or no coffee ( $≤$ 1 cup per day) werecompared with event rates for those consuming greater amountsof coffee. The studies exhibited heterogeneity of results. Thetypical odds ratios and 95% confidence intervals across studieswere estimated by logistic regression analysis. Coffee intakefrom 1 to 4 cups per day was not associated with any increasein coronary heart disease occurrence compared with 1 cup orless per day (odds ratio, 1.01; confidence interval [0.93,1.11]).The odds ratios for 4 to 6 and 6 cups or more per day comparedwith up to 1 cup per day were 1.01 (0.90,1.12) and 1.09 (0.97,1.22),respectively.

Conclusions.—
There is no association between coffee consumption and the occurrenceof coronary heart disease. This conclusion holds in the absenceof adjustment for other coronary risk factors.

(Arch Intern Med. 1992;152:1767-1772)

Author Affiliations

From the Departments of Medicine (Dr Myers) and Clinical Epidemiology (Dr Basinski), Sunnybrook Health Science Centre and Departments of Medicine (Dr Myers) and Family and Community Medicine (Dr Basinski), University of Toronto, Ontario.

Footnotes

Accepted for publication March 20, 1992.

Reprint requests to the Division of Cardiology, Sunnybrook HealthScience Centre, 2075 Bayview Ave, Toronto, Ontario, Canada M4N3M5 (Dr Myers).

Add to CiteULike CiteULike Add to Connotea Connotea Add to Delicious Delicious Add to Digg Digg Facebook Add to Reddit Reddit Add to Technorati Technorati Twitter What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Coffee Consumption and Incidence of Heart Failure in Women
Levitan et al.
Circ Heart Fail 2011;4:414-418.
ABSTRACT | FULL TEXT

Coffee Consumption and Coronary Calcification: The Rotterdam Coronary Calcification Study
van Woudenbergh et al.
Arterioscler. Thromb. Vasc. Bio. 2008;28:1018-1023.
ABSTRACT | FULL TEXT

Coffee Consumption and Risk of Cardiovascular Events After Acute Myocardial Infarction: Results From the GISSI (Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico)-Prevenzione Trial
Silletta et al.
Circulation 2007;116:2944-2951.
ABSTRACT | FULL TEXT

Coffee Consumption and Risk of Myocardial Infarction among Older Swedish Women
Rosner et al.
Am J Epidemiol 2007;165:288-293.
ABSTRACT | FULL TEXT

Coffee Consumption and Coronary Heart Disease in Men and Women: A Prospective Cohort Study
Lopez-Garcia et al.
Circulation 2006;113:2045-2053.
ABSTRACT | FULL TEXT

Coffee, CYP1A2 Genotype, and Risk of Myocardial Infarction
Cornelis et al.
JAMA 2006;295:1135-1141.
ABSTRACT | FULL TEXT

Coffee Drinking Is Dose-Dependently Related to the Risk of Acute Coronary Events in Middle-Aged Men
Happonen et al.
J. Nutr. 2004;134:2381-2386.
ABSTRACT | FULL TEXT

Effect of Caffeine on Blood Pressure Beyond the Laboratory
Myers
Hypertension 2004;43:724-725.
FULL TEXT

Misclassification of Exposure: Coffee as a Surrogate for Caffeine Intake
Brown et al.
Am J Epidemiol 2001;153:815-820.
ABSTRACT | FULL TEXT

Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use
Fredholm et al.
Pharmacol. Rev. 1999;51:83-133.
ABSTRACT | FULL TEXT

Coffee Consumption and Coronary Heart Disease in Women: A Ten-Year Follow-up
Willett et al.
JAMA 1996;275:458-462.
ABSTRACT

The Relationship of Coffee Consumption to Various Self-Reported Cardiovascular Events in Middle-Aged Norwegian Men and Women
Stensvold and Tverdal
Scand J Public Health 1995;23:103-109.
ABSTRACT

Coffee and Coronary Heart Disease
Klatsky et al.
Arch Intern Med 1993;153:902-902.
ABSTRACT

Coffee and Coronary Heart Disease-Reply
Basinski and Myers
Arch Intern Med 1993;153:902-902.
ABSTRACT

| | |