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Thomas W. Boyden, MD; Richard W. Pamenter, PhD; Scott B. Going, PhD; Timothy G. Lohman, PhD; Matthew C. Hall, MS; Linda B. Houtkooper, PhD; Joy C. Bunt, PhD; Cheryl Ritenbaugh, PhD; Mikel Aickin, PhD

Arch Intern Med. 1993;153(1):97-100.

Abstract
Background
Aerobic exercise training is associated with reduced serum concentrations of triglycerides, increased concentrations of high-density lipoprotein cholesterol, and minimal changes in serum levels of total cholesterol or low-density lipoprotein cholesterol. There are few data on the effects of resistance exercise on blood lipid levels.

Methods
Premenopausal women were randomly assigned to a supervised resistance exercise training program (n=46) or a control group (n=42) for 5 months. Serum was analyzed for levels of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglycerides. Body composition and dietary intake were also measured.

Results
The exercise group showed a 0.33±0.03-mmol/L (mean ± SE) decrease in total cholesterol level and a 0.36±0.001-mmol/L decrease in low-density lipoprotein cholesterol level that was significantly different from the control group. No significant changes were noted in serum high-density lipoprotein cholesterol or triglyceride levels in either group. Changes in body composition showed no significant correlations with changes in total cholesterol or low-density lipoprotein cholesterol. There were no significant differences in nutrient intake between the groups.

Conclusion
In healthy, premenopausal women, with normal baseline lipid profiles, 5 months of resistance exercise training was associated with significant decreases in serum total cholesterol and low-density lipoprotein cholesterol concentrations.

(Arch Intern Med. 1993;153:97-100)

Author Affiliations
From the Department of Veterans Affairs Medical Center, Tucson, Ariz (Drs Boyden and Pamenter); and Departments of Exercise and Sports Sciences (Drs Going, Lohman, and Bunt and Mr Hall), Nutrition and Food Science (Dr Houtkooper), and Family and Community Medicine (Drs Ritenbaugh and Aickin), University of Arizona, Tucson.

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