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  Vol. 153 No. 9, 10 MAY 1993 TABLE OF CONTENTS
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Fluconazole-Resistant Candida albicans After Long-term Suppressive Therapy

Ana Sanguineti, MD; J. Kevin Carmichael, MD, MS; Kim Campbell, PharmD

Arch Intern Med. 1993;153(9):1122-1124.


Abstract



Candida albicans is generally considered to be susceptible, in vivo, to fluconazole. In the population infected with human immunodeficiency virus, recurrent bouts of oral and esophageal candidiasis have led to increasing use of fluconazole for long-term prophylaxis. With prolonged therapy, the issue of developing resistance emerges. We report a case of fluconazole-resistant C albicans esophagitis that developed after fluconazole was used for more than 600 days.

(Arch Intern Med. 1993;153:1122-1124)



Author Affiliations



From the Department of Internal Medicine, Tucson (Ariz) Hospital Medical Education Program (Dr Sanguineti); the Department of Internal Medicine, Section of Infectious Disease, Department of Family Medicine, University of Arizona College of Medicine (Dr Carmichael); and the College of Pharmacy, University of Arizona, Tucson (Dr Campbell).



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