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Marco A. Rizzo, MD, PhD; Marc Fisher, MD; J. Paul Lock, MD

Arch Intern Med. 1993;153(9):1130-1132.

Abstract
We treated a case of iatrogenic hypermagnesemia that clinically mimicked a central brain-stem herniation syndrome. Hypermagnesemia (magnesium level, 9.85 mmol/L [24 mg/dL]) can cause parasympathetic blockade, inducing fixed and dilated pupils, in addition to neuromuscular blockade. Extreme hypermagnesemia can therefore mimic a midbrain syndrome and cause a pseudocomatose state.

(Arch Intern Med. 1993;153:1130-1132)

Author Affiliations
From the Departments of Neurology (Drs Rizzo and Fisher) and Medicine (Dr Lock), The Medical Center of Central Massachusetts and University of Massachusetts Medical School, Worcester.

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