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A Case Report With Prolonged Cholinesterase Inhibition and Improvement After Pralidoxime Therapy

Jefferey L. Burgess, MD; Jeffrey N. Bernstein, MD; Katherine Hurlbut, MD

Arch Intern Med. 1994;154(2):221-224.

Abstract
Aldicarb is the most potent of the commercially available carbamate pesticides and is an unusual source of acute human poisonings. We present the case of a 43-year-old man exposed to aldicarb who developed severe cholinergic symptoms and progressive weakness requiring intubation for 5 days. Both his red blood cell cholinesterase and plasma pseudocholinesterase levels were depressed for a minimum of 44 hours. He demonstrated neuromuscular improvement concurrent with pralidoxime administration. The pertinent medical literature on aldicarb poisoning is reviewed.

(Arch Intern Med. 1994;154:221-224)

Author Affiliations
From the Section of Emergency Medicine, University of Arizona Health Sciences Center, Tucson. Dr Hurlbut is now with the Denver (Colo) General Hospital.

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