This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Sidney Goldstein, MD

Arch Intern Med. 1996;156(12):1267-1276.

Abstract
β -Blockers are widely used in cardiovascular medicine. In patients with hypertension, β-blockers show beneficial effects on clinical end points of stroke and coronary heart disease prevention and mortality. β-Blockers also are well established in improving exercise tolerance and decreasing the number and duration of anginal attacks in patients with angina pectoris. Based on evidence showing reduced mortality and morbidity, β-blockers are the cornerstone of therapy after acute myocardial infarction. Unfortunately, presumption of poor tolerance has left these drugs underutilized in this clinical setting, despite data that indicate a wide range of tolerability. The use of β-blockers in patients with congestive heart failure results in beneficial hemodynamic effects and symptomatic improvement. Among factors that should be considered when selecting a β-blocker for an individual patient are demonstrated efficacy of the drug in a specific indication, tolerability, product formulation and duration of action, and the presence or absence of specific properties such as cardioselectivity.

(Arch Intern Med. 1996;156:1267-1276)

Author Affiliations
From the Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, Mich.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Atenolol Hepatotoxicity: Report of a Complicated Case
Dumortier et al.
The Annals of Pharmacotherapy 2009;43:1719-1723.
ABSTRACT | FULL TEXT  

Outcomes of Inappropriate Prescribing of {beta}-Blockers After an Acute Myocardial Infarction in a Medicaid Population
Fernandes et al.
The Annals of Pharmacotherapy 2005;39:1416-1422.
ABSTRACT | FULL TEXT  

Cardiac Rehabilitation and Secondary Prevention of Coronary Heart Disease: An American Heart Association Scientific Statement From the Council on Clinical Cardiology (Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention) and the Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity), in Collaboration With the American Association of Cardiovascular and Pulmonary Rehabilitation
Leon et al.
Circulation 2005;111:369-376.
ABSTRACT | FULL TEXT  

The Impact of a Cardioprotective Protocol on the Incidence of Cardiac Complications After Aortic Abdominal Surgery
Licker et al.
Anesth. Analg. 2002;95:1525-1533.
ABSTRACT | FULL TEXT  

The Treatment of Hypertension in Adult Patients With Diabetes
Arauz-Pacheco et al.
Diabetes Care 2002;25:134-147.
FULL TEXT  

Hyperthyroidism induced by beta-human chorionic gonadotrophin.
JOLOBE
Postgrad. Med. J. 2001;77:423-423.
FULL TEXT  

Management of patients with myocardial infarction and hypertension
Lip et al.
Eur Heart J 2000;21:1125-1134.
 

National Patterns and Predictors of {beta}-Blocker Use in Patients With Coronary Artery Disease
Wang and Stafford
Arch Intern Med 1998;158:1901-1906.
ABSTRACT | FULL TEXT  

beta Adrenergic blockers lower renin in patients treated with ACE inhibitors and diuretics
Holmer et al.
Heart 1998;80:45-48.
ABSTRACT | FULL TEXT