Doxycycline Revisited

doi:10.1001/archinte.1997.00440340035003

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Vol. 157 No. 13, 14 JULY 1997

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Doxycycline Revisited

Nirmal Joshi, MD; Debra Q. Miller, MD

Arch Intern Med. 1997;157(13):1421-1428.

Abstract

Although several new antibiotics have recently become available,in several clinical instances conventional antibiotics may beequally efficacious at a considerably lower cost. In today'sera of cost containment, it is particularly relevant to revisitolder, inexpensive antibiotics to reexplore their role in theface of the emergence of resistant microorganisms and competitionfrom newer agents. Doxycycline is one such antibiotic. It isan inexpensive, broad-spectrum antimicrobial agent that remainsthe drug of first choice for several infections. In addition,it can be used for a variety of other indications. Adverse effectsare infrequent and relatively minor. While interactions occurwith several medications, none of these interactions has significantadverse consequences.

Arch Intern Med. 1997;157:1421-1428

Author Affiliations

From the Division of General Internal Medicine, Department of Medicine, Pennsylvania State University, Hershey.

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