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  Vol. 157 No. 4, 24 FEBRUARY 1997 TABLE OF CONTENTS
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Drugs and Myasthenia Gravis

An Update

Eric T. Wittbrodt, PharmD

Arch Intern Med. 1997;157(4):399-408.


Abstract

Myasthenia gravis is a disease of the neuromuscular junction in which normal transmission of the neuron-to-muscle impulse is impaired or prevented by acetylcholine receptor antibodies. Several classes of drugs have been associated with clinical worsening of existing myasthenia gravis, and a small subset of drugs, most notably the antirheumatic agent penicillamine, have been implicated in the pathogenesis of a variant of the disease. Recent case reports and other documented evidence link a number of specific agents with clinical worsening of myasthenia gravis.

Arch Intern Med. 1997;157:399-408



Author Affiliations

From the Department of Pharmacy Practice and Pharmacy Administration, Philadelphia College of Pharmacy and Science, Philadelphia, Pa.



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