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Arthur Leibovitz, MD; Tamara Bilchinsky, MD; Israel Gil, MD; Beni Habot, MD

Arch Intern Med. 1998;158:1152-1153.

After her daughter died, depression developed in a 93-year-old woman with congestive heart failure receiving digoxin therapy. After treatment with fluoxetine hydrochloride she became anorexic and her serum digoxin level increased. A possible interaction, which has not been reported in the literature, may have occurred between fluoxetine and digoxin.

From the Shmuel Harofe Hospital, Geriatric Medical Center, Beer-Yacov, Israel (Dr Bilchinsky); and the Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel (Drs Leibovitz, Gil, and Habot).

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