 |
|
Depressed Mood and Survival in Seriously Ill Hospitalized Adults
Mary Joan Roach, PhD;
Alfred F. Connors, MD;
Neal V. Dawson, MD;
Neil S. Wenger, MD;
Albert W. Wu, MD, MPH;
Joel Tsevat, MD, MPH;
Norman Desbiens, MD;
Kenneth E. Covinsky, MD, MPH;
Daniel S. P. Schubert, MD, PhD;
for the SUPPORT Investigators
Arch Intern Med. 1998;158:397-404.
Objectives To assess the relationship among depressed mood, physical functioning, and severity of illness and to determine the relationship between depressed mood and survival time, controlling for severity of illness, baseline functioning, and characteristics of patients.
Methods Prospective cohort study of data for 3529 seriously ill hospitalized adults who received care at 5 tertiary care teaching hospitals and who completed a depressed mood assessment 7 to 11 days after admission to the study. The Profile of Mood States depression subscale was used to assess depressed mood. A stratified Cox proportional hazards model was used to assess the independent effect of depressed mood on survival time, adjusting for demographic characteristics of patients and health status.
Results Greater magnitudes of depressed mood were associated with worse levels of physical functioning (r=0.151; P<.001) and more severity of illness. Depressed mood was associated with reduced survival time after adjusting for patient demographics and health status (hazards ratio, 1.134; 95% confidence interval, 1.071-1.200; P .001).
Conclusion Seriously ill patients should be assessed for the presence of depressed mood even if they have not been given a diagnosis of depression. Further study is needed to determine whether interventions aimed at relieving depressed mood may improve prognosis.
From the MetroHealth Medical Center and Case Western Reserve University School of Medicine, Cleveland, Ohio (Drs Roach, Dawson, and Schubert); the University of Virginia School of Medicine at Charlottesville (Dr Connors); the University of California at Los Angeles (Dr Wenger); The Johns Hopkins University, Baltimore, Md (Dr Wu); the University of Cincinnati Medical Center, Cincinnati, Ohio (Dr Tsevat); the University of Tennessee College of Medicine, Chattanooga Unit (Dr Desbiens); and the University Hospitals of Cleveland, Cleveland, Ohio (Dr Covinsky).
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
|
Geriatric Syndromes in Elderly Patients Admitted to an Oncology-Acute Care for Elders Unit
Flood et al.
JCO 2006;24:2298-2303.
ABSTRACT
| FULL TEXT
Are Preoperative Depressive Symptoms Associated With Postoperative Delirium in Geriatric Surgical Patients?
Leung et al.
J. Gerontol. A Biol. Sci. Med. Sci. 2005;60:1563-1568.
ABSTRACT
| FULL TEXT
Barriers to the Treatment of Depression in Cancer Patients
Greenberg
J Natl Cancer Inst Monogr 2004;2004:127-135.
ABSTRACT
| FULL TEXT
New Postoperative Depressive Symptoms and Long-Term Cardiac Outcomes After Coronary Artery Bypass Surgery
Peterson et al.
AJGP 2002;10:192-198.
ABSTRACT
| FULL TEXT
Depressive Symptoms as a Predictor of 6-Month Outcomes and Services Utilization in Elderly Medical Inpatients
Bula et al.
Arch Intern Med 2001;161:2609-2615.
ABSTRACT
| FULL TEXT
Brief Communication: Detecting Depression: Providing High Quality Primary Care for HIV-Infected Patients
Fairfield et al.
American Journal of Medical Quality 2001;16:71-74.
ABSTRACT
Medical Illness, Past Depression, and Present Depression: A Predictive Triad for In-Hospital Mortality
Cavanaugh et al.
Am. J. Psychiatry 2001;158:43-48.
ABSTRACT
| FULL TEXT
Association Between Depressive Symptoms and Mortality in Medical Inpatients
Furlanetto et al.
Psychosomatics 2000;41:426-432.
ABSTRACT
| FULL TEXT
Does Depression Kill?
Wulsin
Arch Intern Med 2000;160:1731-1732.
FULL TEXT
Depressive Symptoms and 3-Year Mortality in Older Hospitalized Medical Patients
Covinsky et al.
ANN INTERN MED 1999;130:563-569.
ABSTRACT
| FULL TEXT
A Systematic Review of the Mortality of Depression
Wulsin et al.
Psychosom. Med. 1999;61:6-17.
ABSTRACT
| FULL TEXT
Depression was associated with decreased survival for hospital patients who were seriously ill
Dyer
Evid. Based Nurs. 1998;1:127-127.
FULL TEXT
OTHER ARTICLES NOTED
Evid. Based Ment. Health 1998;1:67-67.
FULL TEXT
|
