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Barbara Phillips, MD, MSPH, FCCP; Terry Young, PhD; Laurel Finn, MS; Karen Asher, BA; Wayne A. Hening, MD, PhD; Cheryl Purvis, PhD

Arch Intern Med. 2000;160:2137-2141.

Background  Restless legs syndrome (RLS) is a disorder characterized by sleep-disrupting unpleasant leg sensations, often accompanied by daytime behavioral problems. Treatment for this condition is available, but it is suspected that most instances of RLS remain undiagnosed. The goal of this investigation was to assess the prevalence and health status correlates of restless legs symptoms (hereinafter referred to as restless legs) in the general population.

Methods  A question reflecting the clinical features of RLS was added to the 1996 Kentucky Behavioral Risk Factor Surveillance Survey. Data on the frequency of experiencing restless legs, self-rated general and mental health status, demographics, and behavioral risk factors were collected by telephone interview from 1803 men and women, 18 years and older.

Results  Experiencing restless legs 5 or more nights per month was reported by 3% of participants aged 18 to 29 years, 10% of those aged 30 to 79 years, and 19% of those 80 years and older. The age-adjusted prevalence for Kentucky adults is 10.0%; prevalence did not vary significantly by sex. The adjusted odds ratios (95% confidence intervals) for restless legs and diminished general health and poor mental health status were 2.4 (1.4-4.0) and 3.1 (2.0-4.6), respectively. Restless legs were significantly associated with increased age and body mass index, lower income, smoking, lack of exercise, low alcohol consumption, and diabetes.

Conclusions  The prevalence of restless legs in the general adult population is high. Restless legs may be associated with decreased well-being, emphasizing the need for further research and greater medical recognition of this condition.

From the Departments of Medicine (Dr Phillips) and Anatomy (Dr Purvis), University of Kentucky College of Medicine, Lexington; the Kentucky Cabinet for Health Services, Frankfort (Ms Asher); the Department of Preventive Medicine, University of Wisconsin, Madison (Dr Young and Ms Finn); and the University of Medicine and Dentistry of New Jersey, the Robert Wood Johnson Medical School, and the Veterans Affairs Medical Center, Lyons, NJ (Dr Hening).

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