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Urho M. Kujala, MD; Jaakko Kaprio, MD; Pekka Kannus, MD; Seppo Sarna, PhD; Markku Koskenvuo, MD

Arch Intern Med. 2000;160:705-708.

Background  Physical activity has been related to reduced risk of osteoporotic hip fractures, but the evidence among men is weak.

Objective  To determine the association between baseline leisure physical activity and future risk of osteoporotic hip fracture in men.

Methods  At baseline in 1975 our prospective study cohort included 3262 men who were 44 years or older and did not have chronic disease restricting their ability to exercise. At baseline, physical activity was assessed by a questionnaire. Hip fractures were followed for 21 years, or from the age of 50 years for subjects who were initially younger than 50 years.

Results  The hazard ratio of osteoporotic hip fracture, adjusted for other possible predictors (height, body mass index, baseline diseases, smoking, use of alcohol, work-related physical activity, and occupational group), in men participating in vigorous physical activity compared with men not participating was 0.38 (95% confidence interval, 0.16-0.91) (P=.03).

Conclusion  These results provide further evidence that there is an inverse association between baseline physical activity and future hip fracture risk among men.

From the Unit for Sports and Exercise Medicine, University of Helsinki, Helsinki, Finland (Dr Kujala); the Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki (Dr Kaprio); Accident and Trauma Research Center, Urho Kaleva Kekkonen Institute for Health Promotion Research, Tampere, Finland (Dr Kannus); the Department of Public Health, University of Helsinki (Dr Sarna); and the Department of Public Health, University of Turku, Turku, Finland (Dr Koskenvuo).

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