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  Vol. 161 No. 13, July 9, 2001 TABLE OF CONTENTS
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Weight Control in the Physician's Office

Judith M. Ashley, PhD, RD; Sachiko T. St Jeor, PhD; Jon P. Schrage, MD, MPA; Suzanne E. Perumean-Chaney, MS; Mary C. Gilbertson, PhD, RD; Nanette L. McCall, RD; Vicki Bovee, MS, RD

Arch Intern Med. 2001;161:1599-1604.

Background  Lifestyle changes involving diet, behavior, and physical activity are the cornerstone of successful weight control. Incorporating meal replacements (1-2 per day) into traditional lifestyle interventions may offer an additional strategy for overweight patients in the primary care setting.

Methods  One hundred thirteen overweight premenopausal women (mean ± SD age, 40.4 ± 5.5 years; weight, 82 ± 10 kg; and body mass index, 30 ± 3 kg/m2) participated in a 1-year weight-reduction study consisting of 26 sessions. The women were randomly assigned to 3 different traditional lifestyle-based groups: (1) dietitian-led group intervention (1 hour per session), (2) dietitian-led group intervention incorporating meal replacements (1 hour per session), or (3) primary care office intervention incorporating meal replacements with individual physician and nurse visits (10-15 minutes per visit).

Results  For the 74 subjects (65%) completing 1 year, the primary care office intervention using meal replacements was as effective as the traditional dietitian-led group intervention not using meal replacements (mean ± SD weight loss, 4.3% ± 6.5% vs 4.1% ± 6.4%, respectively). Comparison of the dietitian-led groups showed that women using meal replacements maintained a significantly greater weight loss (9.1% ± 8.9% vs 4.1% ± 6.4%) (P = .03). Analysis across groups showed that weight loss of 5% to 10% was associated with significant (P = .01) reduction in percentage of body fat, body mass index, waist circumference, resting energy expenditure, insulin level, total cholesterol level, and low-density lipoprotein cholesterol level. Weight loss of 10% or greater was associated with additional significant (P = .05) improvements in blood pressure and triglyceride level.

Conclusions  A traditional lifestyle intervention using meal replacements can be effective for weight control and reduction in risk of chronic disease in the physician's office setting as well as in the dietitian-led group setting.


From the Nutrition Education and Research Program (Drs Ashley, St Jeor, Gilbertson, and Bovee and Mss Perumean-Chaney and McCall) and Department of Internal Medicine (Dr Schrage), University of Nevada School of Medicine, Reno.



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