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Septic Thrombosis of the Cavernous Sinuses
John R. Ebright, MD;
Mitchell T. Pace, MD;
Asher F. Niazi, MD
Arch Intern Med. 2001;161:2671-2676.
Septic thrombosis of the cavernous sinuses (or cavernous sinus thrombophlebitis
[CST]) is a dramatic and potentially lethal illness, which is still occasionally
seen by clinicians. Before the availability of antimicrobial agents, mortality
from CST was near 100%, but it markedly decreased to approximately 20% to
30% during the antibiotic era.1-2
Nevertheless, the threat of death and serious morbidity continues to necessitate
early recognition, diagnosis, and treatment of CST to minimize risks to the
patient. Accordingly, we reviewed the salient clinical features of this illness,
with emphasis on newer aspects of diagnosis and treatment.
From the Departments of Medicine (Drs Ebright and Niazi) and Radiology
(Dr Pace), Wayne State University School of Medicine and Detroit Medical Center,
Detroit, Mich.
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