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Hyperthermia and Chronic Pancerebellar Syndrome After Cocaine Abuse
Tawee Tanvetyanon, MD;
Jonathan Dissin, MD;
Uzi M. Selcer, MD
Arch Intern Med. 2001;161:608-610.
We describe a patient who developed pancerebellar syndrome as a result
of hyperthermia that developed after cocaine use. The patient had long-standing
schizophrenia and had been taking risperidone for 2 years, without evidence
of abnormal movements. A literature review revealed a marked similarity between
cocaine and neuroleptics in their ability to cause hyperthermia. Based on
our observations and the compatible evidence from the literature, we suggest
that cocaine use may cause hyperthermia and result in chronic pancerebellar
dysfunction.
From the Departments of Medicine (Dr Tanvetyanon), Neurology (Dr Dissin),
Medicine (Dr Selcer), and Pediatrics (Dr Selcer), Albert Einstein Medical
Center, Philadelphia, Pa.
Corresponding author: Tawee Tanvetyanon, MD, Department of Medicine,
Albert Einstein Medical Center, Klein 3, 5501 Old York Rd, Philadelphia, PA
19141 (e-mail: tanvetyt{at}aehn2.einstein.edu).
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