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Brugada Syndrome
An Unusual Cause of Convulsive Syncope
Hakan Paydak, MD;
E. Andrew Telfer, MD;
Richard F. Kehoe, MD;
Priya Balasubramanian, MD;
Leela Narra, MD;
Marilyn Ezri, MD;
Terry Zheutlin, MD;
Pradeep Maheshwari, MD;
Jose Nazari, MD;
Theodore Wang, MD
Arch Intern Med. 2002;162:1416-1419.
A patient who presented with a new apparent seizure was found to have
abnormal electrocardiographic findings, with classic features of the Brugada
syndrome. He had spontaneous episodes of nonsustained ventricular tachycardia,
easily inducible ventricular fibrillation at electrophysiological study in
the absence of structural heart disease, and a negative neurological evaluation.
These findings suggested that sustained ventricular arrhythmias known to be
associated with the Brugada syndrome and resultant cerebral hypoperfusion,
rather than a primary seizure disorder, were responsible for the event. Patients
with the Brugada syndrome often present with sudden death or with syncope
resulting from ventricular arrhythmias. In consideration of its variability
in presentation sometimes mimicking other disorders, primary care physicians
and internists should be aware of its often transient electrocardiographic
features.
From the Departments of Medicine, Case Western Reserve University,
University Hospitals of Cleveland, Cleveland, Ohio (Dr Paydak), and Advocate
Illinois Masonic Medical Center, Chicago, Ill (Drs Telfer, Kehoe, Balasubramanian,
Narra, Ezri, Zheutlin, Maheshwari, Nazari, and Wang).
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ABSTRACT
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