Massive Bleeding on a Bladder Protectant
A Case Report of Pentosan Polysulfate Sodium–Induced Coagulopathy
Sharlene Gill, MD;
Sheldon C. Naiman, MD;
Abeed Jamal, MD;
Linda M. Vickars, MD
Arch Intern Med. 2002;162:1644-1645.
Pentosan polysulfate sodium (Elmiron; Alza Pharmaceuticals, Mountain
View, Calif) is an oral preparation of pentosan polysulfate used in the symptomatic
management of interstitial cystitis. While pentosan polysulfate has a known
heparinlike effect in its parenteral form, there have been no previous reports
of coagulopathy with oral use. We present an interesting case of inadvertent
systemic anticoagulation resulting in serious bleeding complications in a
young woman taking oral pentosan polysulfate for interstitial cystitis.
From the Department of Medicine, University of British Columbia (Drs
Gill and Jamal); and the Division of Clinical Hematology, St Paul's Hospital
(Drs Naiman and Vickars), Vancouver, British Columbia.
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Misleading Report of Massive Bleeding in a Patient Taking Pentosan Polysulfate
C. Lowell Parsons
Arch Intern Med. 2003;163(1):119.
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Misleading Report of Massive Bleeding in a Patient Taking Pentosan Polysulfate
Sharlene Gill, Sheldon C. Naiman, Abeed Jamal, and Linda M. Vickars
Arch Intern Med. 2003;163(1):119.
EXTRACT
| FULL TEXT
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Misleading Report of Massive Bleeding in a Patient Taking Pentosan Polysulfate
Parsons
Arch Intern Med 2003;163:119-119.
FULL TEXT
Misleading Report of Massive Bleeding in a Patient Taking Pentosan Polysulfate
Gill et al.
Arch Intern Med 2003;163:119-119.
FULL TEXT
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