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Bilateral External Laryngoceles Following Radioiodine Ablation for Graves Disease
Derek J. Stocker, MD;
William F. Kelly, MD;
Thomas M. Fitzpatrick, MD;
Victor J. Bernet, MD;
Henry B. Burch, MD
Arch Intern Med. 2002;162:2007-2009.
A 28-year-old trumpet player underwent multiple treatments with radioactive
iodine for Graves disease associated with an unusually large goiter. Following
his second treatment, the patient developed acute neck pain and swelling.
Radiographic studies and a laryngoscopy demonstrated bilateral symptomatic
external laryngoceles, a very rare entity, not previously known to be associated
with radioiodine treatment or Graves disease. The patient's profession placed
him at risk for the development of a laryngocele, but the temporal relationship
to goiter regression following radioiodine therapy suggests that this occurred
as a result of this treatment. The patient's disease was managed nonsurgically,
and he has subsequently done well. This represents the first known association
of symptomatic laryngocele with radioiodine treatment for Graves disease.
From the Endocrine-Metabolic Service (Drs Stocker, Bernet, and Burch)
and Pulmonary–Critical Care Service (Drs Kelly and Fitzpatrick), Department
of Medicine, Walter Reed Army Medical Center, Washington, DC.
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