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Is High-Sensitivity C-Reactive Protein an Effective Screening Test for Cardiovascular Risk?
Arch Intern Med. 2002;162:867-869.
We evaluate the suggestion that high-sensitivity C-reactive protein
testing be used for risk assessment in the primary prevention of cardiovascular
disease, using the criteria proposed by the Guide to Clinical
Preventive Services developed by the US Preventive Services Task Force.
We conclude that at present, none of the 3 major criteria—accuracy,
reliability, and likelihood of beneficial intervention— are satisfied.
Irving Kushner, MD;
Ashwini R. Sehgal, MD
From the Departments of Medicine (Drs Kushner and Sehgal), Pathology
(Dr Kushner), and Epidemiology and Biostatistics (Dr Sehgal) and Center for
Biomedical Ethics (Dr Sehgal), Case Western Reserve University; and Division
of Nephrology and Center for Health Care Research and Policy, MetroHealth
Medical Center (Dr Sehgal), Cleveland, Ohio.
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Arch Intern Med. 2002;162(19):2249-2251.
EXTRACT
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RELATED ARTICLE
Archives of Internal Medicine Reader's Choice: Continuing Medical Education
Arch Intern Med. 2002;162(8):951-952.
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