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A Risk Factor for Accidental Drug Overdose

Matthias Schwab, MD; Carsten Oetzel, MD; Klaus Mörike, MD; Christine Jägle, MD; Christoph H. Gleiter, MD; Michel Eichelbaum, MD

Arch Intern Med. 2002;162:1065-1066.

Medication errors due to the exclusive use of trade names of drugs may lead to life-threatening complications. We report the case of a patient with verapamil overdose as a result of this. This case illustrates that the use of trade names, omitting the international nonproprietary names of the active moiety, carries the risk of serious adverse drug events by overdose.

From the Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart (Drs Schwab and Eichelbaum), Robert Bosch Hospital, Center of Internal Medicine, Stuttgart (Dr Oetzel), and the Division of Clinical Pharmacology, University Hospital Tübingen, Tübingen (Drs Mörike, Jägle, Gleiter, and Eichelbaum), Germany.

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