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David A. Rapko, MD; Darius A. Rastegar, MD

Arch Intern Med. 2003;163:367-368.

Clonidine hydrochloride is an ₂-adrenergic agonist commonly prescribed as an antihypertensive agent. It is also useful in ameliorating symptoms associated with opiate withdrawal and is frequently used in the detoxification setting. We report an episode in which 3 normotensive patients each ingested a single 0.1-mg clonidine patch in a detoxification unit.

From the Department of Medicine, Johns Hopkins Bayview Medical Center, Baltimore, Md.