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A Clinical Review

W. Andrew Oldenburg, MD; L. Louis Lau, MD; Thomas J. Rodenberg, MD; Hope J. Edmonds, MD; Charles D. Burger, MD

Arch Intern Med. 2004;164:1054-1062.

Acute mesenteric ischemia is a life-threatening vascular emergency that requires early diagnosis and intervention to adequately restore mesenteric blood flow and to prevent bowel necrosis and patient death. The underlying cause is varied, and the prognosis depends on the precise pathologic findings. Despite the progress in understanding the pathogenesis of mesenteric ischemia and the development of modern treatment modalities, acute mesenteric ischemia remains a diagnostic challenge for clinicians, and the delay in diagnosis contributes to the continued high mortality rate. Early diagnosis and prompt effective treatment are essential to improve the clinical outcome.

From the Section of Vascular Surgery (Drs Oldenburg and Lau), the Department of Critical Care (Dr Rodenberg), and the Divisions of Endocrinology (Dr Edmonds) and Pulmonary Medicine (Dr Burger), Mayo Clinic, Jacksonville, Fla. The authors have no relevant financial interest in this article.

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