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  Vol. 166 No. 17, September 25, 2006 TABLE OF CONTENTS
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Cost-Related Medication Nonadherence Among Elderly and Disabled Medicare Beneficiaries

A National Survey 1 Year Before the Medicare Drug Benefit

Stephen B. Soumerai, ScD; Marsha Pierre-Jacques, BA; Fang Zhang, PhD; Dennis Ross-Degnan, ScD; Alyce S. Adams, PhD; Jerry Gurwitz, MD; Gerald Adler, MPhil; Dana Gelb Safran, ScD

Arch Intern Med. 2006;166:1829-1835.

Background  Prior to implementation of the Medicare drug benefit, we estimated the prevalence of cost-related medication nonadherence (CRN) among Medicare enrollees, including elderly and nonelderly disabled beneficiaries.

Methods  In the fall of 2004, detailed measures of CRN (skipping or reducing doses or not filling prescriptions because of cost) were added to the Medicare Current Beneficiary Survey. We examined the prevalence of CRN nationally and by Medicare eligibility subgroups (elderly vs nonelderly disabled beneficiaries), drug coverage status, socioeconomic status, self-rated health, and number of chronic medical conditions.

Results  In a national sample of 13 835 noninstitutionalized Medicare enrollees, 29% of the disabled and 13% of the elderly beneficiaries reported CRN; those in fair to poor health with multiple comorbidities and without coverage were most at risk. Among the disabled enrollees with 4 or more morbidities, 52% (95% confidence interval [CI], 43.3%-60.3%) without drug coverage skipped prescriptions or doses compared with 26% (95% CI, 17.7%-34.8%) with Medicaid drug coverage. Those with partial drug coverage through Medigap policies or Medicare health maintenance organizations reported intermediate rates of CRN. The adjusted odds ratio of CRN among disabled enrollees in poor (vs good) health was 3.9 (95% CI, 1.7-9.2), whereas for those with 4 or more (vs <4) comorbidities, the odds ratio of CRN was 2.7 (95% CI, 1.7-4.1).

Conclusions  One year before Medicare Part D implementation, Medicare beneficiaries reported high rates of CRN. Rates are highest among nonelderly disabled beneficiaries, but among both elderly and disabled beneficiaries, CRN is exacerbated by poor health, multiple morbidities, and limited drug coverage. Given the high cost sharing under Part D, it is important to closely monitor CRN in high-risk subgroups.


Author Affiliations: Department of Ambulatory Care and Prevention, Harvard Medical School & Harvard Pilgrim Health Care, Boston, Mass (Drs Soumerai, Zhang, Ross-Degnan, and Adams and Ms Pierre-Jacques); Meyers Primary Care Institute and University of Massachusetts Medical School, Worcester (Dr Gurwitz); Centers for Medicare and Medicaid Services, US Department of Health and Human Services, Baltimore, Md (Mr Adler); and The Health Institute at Tufts–New England Medical Center and Tufts University School of Medicine, Boston (Dr Safran).


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