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  Vol. 167 No. 19, October 22, 2007 TABLE OF CONTENTS
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Use of a Case Manager to Improve Osteoporosis Treatment After Hip Fracture

Results of a Randomized Controlled Trial

Sumit R. Majumdar, MD, MPH; Lauren A. Beaupre, PhD; Charles H. Harley, MD; David A. Hanley, MD; Douglas A. Lier, MA; Angela G. Juby, MB, ChB; Walter P. Maksymowych, MD; John G. Cinats, MD; Neil R. Bell, MD; Donald W. Morrish, MD, PhD

Arch Intern Med. 2007;167(19):2110-2115.

Background  Patients who survive hip fracture are at high risk of recurrent fractures, but rates of osteoporosis treatment 1 year after sustaining a fracture are less than 10% to 20%. We have developed an osteoporosis case manager intervention. The case manager educated patients, arranged bone mineral density tests, provided prescriptions, and communicated with primary care physicians. The intervention was compared with usual care in a randomized controlled trial.

Methods  We recruited from all hospitals that participate in the Capital Health system (Alberta, Canada), including patients 50 years or older who had sustained a hip fracture and excluding those who were receiving osteoporosis treatment or who lived in a long-term care facility. Primary outcome was bisphosphonate therapy 6 months after fracture; secondary outcomes included bone mineral density testing, appropriate care (bone mineral density testing and treatment if bone mass was low), and intervention costs.

Results  We screened 2219 patients and allocated 220, as follows: 110 to the intervention group and 110 to the control group. Median age was 74 years, 60% were women, and 37% reported having had previous fractures. Six months after hip fracture, 56 patients in the intervention group (51%) were receiving bisphosphonate therapy compared with 24 patients in the control group (22%) (adjusted odds ratio, 4.7; 95% confidence interval, 2.4-8.9; P < .001). Bone mineral density tests were performed in 88 patients in the intervention group (80%) vs 32 patients in the control group (29%) (P < .001). Of the 120 patients who underwent bone mineral density testing, 25 (21%) had normal bone mass. Patients in the intervention group were more likely to receive appropriate care than were patients in the control group (67% vs 26%; P < .001). The average intervention cost was $50.00 per patient.

Conclusion  For a modest cost, a case manager was able to substantially increase rates of osteoporosis treatment in a vulnerable elderly population at high risk of future fractures.

Trial Registration  clinicaltrials.gov Identifier: NCT00175175


Author Affiliations: Departments of Medicine (Drs Majumdar, Harley, Juby, Maksymowych, and Morrish), Surgery (Drs Beaupre and Cinats), and Family Medicine (Dr Bell) and the Institute of Health Economics (Dr Majumdar and Mr Lier), University of Alberta, Edmonton, Alberta, Canada; and the Department of Medicine, University of Calgary, Calgary, Alberta, Canada (Dr Hanley).



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