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The articles by Brooks and McGee¹ and Gonzalez-Gay et al² describe the diagnostic dilemmas associated with polymyalgia rheumatica (PMR), especially in patients with atypical features and a normal erythrocyte sedimentation rate (ESR). Clinically, patients with PMR often present with initial thrombocytosis, a fact that has not been addressed in the literature. To examine the relevance of early thrombocytosis in PMR, we performed a retrospective study of 23 patients (14 women and 9 men; mean age, 67.3 years) who fulfilled Bird's diagnostic criteria¹ for PMR after exclusion of individuals with disorders that have similar clinical manifestations, such as infections, malignant neoplasms, and collagen disorders. A prompt response to corticosteroid therapy was documented in all patients. Seven of the patients had biopsy-proved temporal arteritis, clinical details of which are described elsewhere.³ Platelet counts, ESR, and C-reactive protein (CRP) levels were monitored during diagnostic workup and for the first 3 weeks after initiation . . . [Full Text of this Article]

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