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  Vol. 158 No. 10, May 25, 1998 TABLE OF CONTENTS
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Reversible Hypothyroidism With Corticotropin Releasing Hormone Deficiency

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Reversible hypothyroidism after corticosteroid replacement therapy has been reported in association with primary and secondary adrenal insufficiencies (Addison disease1-2 and isolated adrenocorticotropic hormone deficiency3). We report a case of reversible hypothyroidism in a patient diagnosed as having corticotropin releasing hormone deficiency.

Report of a Case

A 72-year-old woman was admitted because of a loss of consciousness induced by hypoglycemia (blood glucose level, 2.3 mmol/L [41 mg/dL]). There was no significant family or personal history of excess iodine intake. Her serum free thyroxine level was 14 pmol/L (1.1 ng/dL) (normal range, 11-27 pmol/L [0.85-2.15 ng/dL]), her free triiodothyronine level was 0.03 pmol/L (normal range, 0.04-0.09 pmol/L), and her thyrotropin level was 32.2 µIU/L (normal range, 0.3-3.5 µIU/L). Basal serum cortisol and adrenocorticotropic hormone levels were 110.4 nmol/L (normal range, 121.4-480.1 nmol/L) and 264.2 nmol/L (normal range, 134.3-1211.1 nmol/L), respectively. Urinary excretion of free cortisol was abnormally low. Basal levels of other hormones (growth hormone, . . . [Full Text of this Article]


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