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The development of adult respiratory distress syndrome (ARDS) after antithymocyte globulin (ATG) administration has not been reported in clinical trials.^1-4 However, Dean et al⁵ report a case in which antilymphocyte globulin was suspected to have caused ARDS in a patient who underwent renal transplantation. We describe herein a case of ARDS that developed as a result of ATG infusion.

A 57-year-old woman with a history of metastatic breast cancer was admitted to our hospital because of fever and pancytopenia. A complete blood cell count revealed the following values: neutrophils, 0.04 x 10⁹/L; hemoglobin, 7.6 gm/dL; hematocrit, 0.22; and platelets, 0.10 x 10⁹/L. Interestingly, the patient's last course of chemotherapy was 5 months prior to her admission. Two weeks prior to admission, her neutrophil count was 0.16 x 10⁹/L and her platelet count was 3.0 x 10⁹/L. Extensive cultures were taken and she started treatment with meropenem . . . [Full Text of this Article]