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We live in the midst of an osteoporosis epidemic. With the population aging, osteoporosis is becoming a major national health issue. While it affects both women and men, only recently has it been gaining attention in men.¹ Still, the problem remains unrecognized by the vast majority of the medical community.

Androgen deprivation is emerging as an important risk factor for osteoporosis in men. Stepan et al² examined a group of 12 men who had undergone bilateral orchiectomy for sexual delinquency up to 11 years before the study. The mean age at orchiectomy was 28 years (age range, 20-42 years).

Significant loss of bone density was observed in all men who had undergone castration. One man developed severe osteoporosis resulting in hip fracture and death 8 years after the procedure. Accelerated bone mass loss was also demonstrated in patients with prostate cancer who were treated with androgen ablation, either pharmacological or . . . [Full Text of this Article]

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