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Hemophagocytic syndrome (HPS) is an infrequent disorder characterized by a benign proliferation of mature histiocytes and uncontrolled phagocytosis of some hematic precursors in the bone marrow. From a clinical point of view, most of the manifestations can be attributed to pancytopenia.^1-2 Hemophagocytic syndrome has been associated with various stimuli, such as infections, malignant neoplasms, and several other immunosuppressive states.^1-2 Human immunodeficiency virus (HIV) infection predisposes to the development of infections and hematologic malignancies and thus to reactive bone marrow phenomena, such as HPS.^3-4 Among infection-associated HPS, Mycobacterium tuberculosis infection has been described as a severe but not infrequent cause. We recently cared for a patient with acquired immunodeficiency syndrome (AIDS) who presented with tuberculosis-associated HPS, and we reviewed the literature on this topic.

Report of a Case

A 53-year-old woman was admitted to the hospital because of fever, chills, and malaise. One week earlier, she had complained of dry cough and dyspnea. Acquired immunodeficiency . . . [Full Text of this Article]

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