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  Vol. 159 No. 10, May 24, 1999 TABLE OF CONTENTS
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Cigarette Smoking: Risk Factor for Venous Thromboembolic Disease?

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Kahn1 reviewed the clinical diagnosis of deep venous thrombosis (DVT) and presented recent epidemiological data on DVT incidence and risk factors. The author also reviewed recently published clinical prediction indexes for DVT2 designed to improve the cost-effectiveness and utility of clinicians' diagnostic assessment of persons suspected of having DVT. Neither Kahn nor the authors of the prediction indexes included cigarette smoking as a risk factor for DVT.

The thrombogenic potential of tobacco smoking has been recognized for more than 30 years.3 Most early studies were poorly designed and gave conflicting results regarding the link between smoking and DVT and venous thromboembolism (VTE). Recent clinical and epidemiological research, however, support this relationship.4-6 In the largest study to date, part of the Nurses' Health Study, Goldhaber et al7 reported that obesity, hypertension, and cigarette smoking were independent predictors of pulmonary embolism. The relative risk of VTE in this study was increased with . . . [Full Text of this Article]



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